If you’re searching for the best IVF clinics in Spain you’re not alone. High-income patients from the US, UK, Canada, Australia, Mexico, the UAE, and Asia are increasingly turning to Spain for fertility care that blends advanced science with compassionate support.
What makes Spain, such a trusted destination? It's the combination of cutting-edge reproductive technology, exceptional success rates, legal protections for patients, and a healthcare culture that respects your privacy, autonomy, and time.
Among the many options, there are two leading fertility clinics renowned for delivering outstanding IVF and fertility treatments in Spain, Clínica Tambre in Madrid and Dexeus University Hospital in Barcelona.
These fertility centres have helped thousands of hopeful parents from around the world, combining medical excellence with a personal, supportive approach.
You’ll find real success rates, innovative treatments, and answers to the most pressing questions about IVF in Spain.
1. Clínica Tambre, Madrid, Spain
Clínica Tambre in Madrid has 45+ years of experience in assisting patients in need of advanced reproductive medicine services.
Founded in 1978, Clínica Tambre is one of Spain’s most established fertility clinics helping over 10,000 families to have children.
The clinic was a pioneer in Spain’s fertility field; its founder Dr. Pedro Caballero Peregrín even helped draft the country’s first assisted reproduction law.
This long history translates into deep expertise and trustworthiness. Tambre’s results are audited by the Spanish Fertility Society (SEF) and external certifiers, ensuring transparency and quality control.
I. Success Rates and Patient Outcomes
According to verified data shared with Spain’s national fertility registry (SEF), around 70% of patients get pregnant after just one embryo transfer when using their own eggs, this is well above average.
For women over 40, the clinic offers advanced genetic testing (called PGT-A) to check embryo health. With this approach, about 76% of transfers lead to pregnancy, even in older age groups.
Patients using donor eggs also have a strong chance of success. About 67% of embryo transfers result in pregnancy, and when trying up to three times, over 90% of patients become pregnant.
Tambre also follows a single-embryo transfer policy. This means only one embryo is transferred at a time, which lowers the chance of twins or triplets.
Their multiple pregnancy rate is under 1%, making treatment safer for both the parent and the baby. These results show that Tambre combines excellent outcomes with a strong focus on patient safety.
II. Advanced Technologies and Treatments
Clínica Tambre stays at the front line of fertility science. Their embryology lab is modern and highly equipped, using the latest technology to improve every step of the IVF process.
These tools help the clinic achieve strong results even in complex fertility cases. Here’s what sets their technology apart:
- GERI® Time-Lapse Incubators
These special incubators allow embryos to develop in a stable environment while being monitored 24/7 with cameras. This helps embryologists select the healthiest embryo without opening the incubator or disturbing its development. - Preimplantation Genetic Testing (PGT)
This test checks embryos for chromosomal problems before transfer. It helps lower the chance of miscarriage and increases the chances of a healthy baby being born. - Specialised Diagnostic Tools
For more complex fertility cases, Tambre offers:- COMET test to examine sperm DNA quality.
- KIR/HLA-C matching for better implantation results.
- ERA, EMMA, and ALICE tests to check if the uterus is ready for implantation and free from harmful bacteria or inflammation.
- Reproductive Immunology Unit
This unit is led by fertility and immune system specialists. It helps patients who have experienced repeated IVF failures or miscarriages by identifying immune-related problems and creating custom treatment plans. - ZyMot Microfluidic Chips
These are used to select the healthiest and most active sperm for ICSI (a form of IVF where a single sperm is injected into an egg). This improves fertilisation chances and embryo quality. - RI Witness™ Electronic Tracking System
A safety system that tracks all patient samples in the lab. It prevents any chance of mix-ups by using barcodes and electronic monitoring at every step.
By combining these tools with expert medical care, Tambre offers patients an advanced, secure, and highly personalised IVF experience.
Whether you are facing unexplained infertility or past IVF failures, this technology allows the clinic to find answers and solutions.
III. Donor Program and Egg Donation
Clínica Tambre offers one of Spain’s most reliable and well-regulated egg donation programs. In Spain, egg and sperm donation is legal, anonymous, and limited to donors under 35, which helps ensure high standards of health and safety.
Tambre follows strict medical and psychological screening to select donors. This includes:
- Genetic testing for inherited conditions
- Full health checks and mental health evaluations
Because the clinic is based in diverse and international Madrid, it can offer donor matches across a broad range of ethnicities, including European, Latin American, African, and Asian backgrounds, a benefit for patients looking for a closer match.
There are no waiting lists for donor eggs or sperm, so treatment can start when you're ready. Tambre also offers flexible IVF donor packages, some of which guarantee a specific number of high-quality embryos.
Success rates for egg donation at Tambre are consistently above the European average. Many patients who had unsuccessful treatments elsewhere have gone on to conceive through Tambre’s donor IVF program.
2. Dexeus University Hospital, Barcelona, Spain
Dexeus University Hospital in Barcelona is a highly respected fertility centre located within a top private women’s hospital. The reproductive medicine department, known as Dexeus Mujer, has a long history of innovation in fertility care.
For 85+ years, the hospital has focused on women’s health. In 1984, it achieved a major milestone, Spain’s first IVF birth.
Four years later, it also led the country’s first successful egg donation pregnancy. These historic moments helped shape Dexeus’s role as a pioneer in assisted reproduction.
Today, Dexeus is backed by a team of more than 100 medical professionals, with specialists in fields like genetics, andrology, and reproductive endocrinology.
The hospital runs one of Europe’s largest IVF labs, carrying out over 3,000 treatment cycles every year. Even with this high volume of patients, the clinic maintains strict quality standards and ensures that each patient receives a personalised care plan.
Being part of a full-service hospital also means that all treatments and related services are available on-site, offering patients peace of mind and comprehensive support throughout their journey.
I. Success Rates and Outcomes
Dexeus University Hospital is widely recognised for helping patients achieve successful pregnancies, including many who have faced failed IVF cycles elsewhere.
Around 1 in 4 of its patients come with a history of unsuccessful treatment, yet with expert care, many go on to conceive.
First-attempt IVF success rates range from 45% to 55% and can reach 56% for women under 35 using fresh embryos.
The clinic’s cumulative success rate after three IVF cycles rises to about 80%, even among older patients or those with complex fertility issues.
For egg donation, where healthy donor eggs are used, Dexeus reports a 50 - 60% pregnancy rate per transfer, with cumulative success reaching up to 85%.
The clinic prioritises safe, healthy pregnancies by favouring single embryo transfers. Being part of a full-service hospital also ensures immediate access to on-site specialists and emergency care if needed an added layer of confidence for international patients.
These strong outcomes reflect Dexeus’s combination of advanced science, decades of experience, and personalised care that empowers individuals and couples to move forward with clarity and hope.
II. Innovative Treatments and Technology
Dexeus Mujer, the fertility centre at Dexeus University Hospital, is known for being one of the first in Spain to adopt cutting-edge fertility treatments.
With decades of experience and strong ties to academic research, the clinic stays at the forefront of reproductive science.
As part of a full-service hospital, Dexeus offers a wide range of treatments and procedures under one roof.
Patients benefit from having access to advanced technology, experienced specialists, and 24/7 medical services throughout their care journey.
Some of the key technologies and innovations at Dexeus include:
- ICSI (Intracytoplasmic Sperm Injection)
A technique where a single sperm is injected directly into an egg, used in cases of male infertility or previous fertilisation failure. - Time-Lapse Embryo Monitoring (DEM)
Allows continuous, real-time observation of embryo development without removing them from the incubator. This helps select the healthiest embryo for transfer. - Preimplantation Genetic Testing (PGT)
Screens embryos for genetic or chromosomal issues, helping reduce the risk of miscarriage and increase the chance of a healthy baby. - ZyMot™ Microfluidic Sperm Selection Chip
Filters and selects the strongest, healthiest sperm, improving fertilisation and embryo quality. - MACS (Magnetic-Activated Cell Sorting)
A lab technique that removes sperm with damaged DNA, increasing success rates for ICSI treatments. - Gidget® Automation System
A smart platform that safely manages the handling of eggs, sperm, and embryos to ensure precision and reduce the chance of lab errors.
Dexeus also supports patients through:
- On-site surgical procedures and diagnostics – such as egg retrievals, hysteroscopies, and fertility scans
- Fertility preservation – including egg freezing and sperm banking
- Clinical research trials – giving some patients early access to new techniques and protocols
The clinic is committed to meeting international quality and safety standards, ensuring that all procedures are carefully monitored and controlled.
Wondering where to start? Get in touch with an international patient support specialist for help in getting IVF and fertility treatment at Dexeus University Hospital
III. Egg Donation and Third-Party Reproduction
Dexeus University Hospital offers a wide range of fertility options, including egg donation and third-party reproduction.
Spain’s legal framework allows single women, unmarried couples, and same sex female couples to access treatment equally, making Dexeus a supportive destination for many international patients.
Key points of their program include:
- Strict donor selection – All egg donors are under 35 and go through medical and genetic screening, in line with Spanish law.
- High success rates – The clinic reports up to 85% pregnancy success with donor eggs after a few cycles.
- Anonymity and ethical care – Donations are anonymous and follow strong ethical and legal standards.
- Reciprocal IVF (ROPA) – Available for lesbian couples, where one partner provides the eggs and the other carries the pregnancy.
- Comprehensive care – As part of a full hospital, Dexeus can handle more complex cases like fertility preservation and advanced male infertility treatment.
- Individual case review – Special medical committees evaluate complex or rare cases to ensure personalised, expert led care.
These services, delivered with professionalism and discretion, help Dexeus support diverse patient needs while maintaining quality, safety, and trust.
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How My 1Health Helps Individuals and Couples Access Fertility Treatment in Spain
Choosing to undergo fertility treatment abroad is a major decision, and at My 1Health, we are committed to making this journey smoother, safer, and more successful for individuals and couples from around the world.
Whether you're seeking IVF, ICSI, egg donation, or advanced fertility diagnostics, our role is to bridge the gap between you and Spain’s top fertility centres, Clínica Tambre in Madrid and Dexeus University Hospital in Barcelona.
Our support begins the moment you contact us. Here’s how we walk with you every step of the way:
1. Personalised Guidance from Day One
From your very first enquiry, you are assigned a dedicated Patient Support Specialist. This experienced professional will be your primary point of contact, helping you understand your treatment options, timelines, and what to expect.
They ensure that your experience is stress free, culturally sensitive, and fully aligned with your personal goals and medical history.
2. Expert Case Review and Medical Coordination
Once you share your medical history and fertility records, we ensure your documents are:
- Handled securely and confidentially
- Reviewed by fertility experts at Clínica Tambre or Dexeus University Hospital
- Matched with the most appropriate specialists and treatment options
Our coordination guarantees that you receive a well-informed medical opinion before taking any steps toward travel.
3. Pre-Treatment Consultations Online
We make it easy to begin your journey from home. Our team will help schedule video consultations with your fertility doctor, allowing you to:
- Ask important questions
- Understand your personalised treatment plan
- Decide confidently about moving forward
This also helps reduce your travel time and ensures that everything is ready before you even board a flight.
4. Full Travel and Visa Support
Planning an international trip for medical care can be overwhelming but we take care of the logistics:
- Visa Assistance: We’ll inform you of all required documents and processes specific to your country of residence
- Flight Booking: Our team recommends the most suitable travel windows based on your treatment timeline
- Accommodation Booking: We help you choose trusted, comfortable, and clinic-adjacent stays
- Arrival and Check-In Support: We ensure smooth coordination with your clinic upon arrival, so nothing feels unfamiliar
5. Post-Treatment Care and Support
Your journey doesn't end after embryo transfer or egg retrieval. We remain by your side to ensure continuity of care:
- Remote follow-up appointments with your doctor
- Support with prescriptions or ongoing medications
- Guidance on next steps whether your cycle is successful or further plans are needed
- Emotional support when needed, because we understand the mental and emotional side of fertility care
